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Year : 2013  |  Volume : 3  |  Issue : 2  |  Page : 126-130

Analysis of hemogram profile of elderly diabetics in a tertiary care hospital

1 Department of Pharmacology, Kasturba Medical College, Manipal University, Mangalore, India
2 Department of Medicine, Kasturba Medical College, Manipal University, Mangalore, India

Correspondence Address:
Nithyananda K Chowta
Department of Medicine, Kasturba Medical College, Manipal University, Light House Hill Road, Mangalore - 575 001
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/2231-0738.112836

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Background: Anemia is a common concern in geriatric health, but its exact incidence and prevalence are unclear. Several studies have addressed this issue with discrepant results. Recent findings have shown that anemia can lead to cardiovascular and neurological complications, such as congestive heart failure and impaired cognitive function. Objective: To evaluate the hemogram profile in elderly diabetic patients and compare the same with younger diabetic patients. Materials and Methods: A retrospective chart review of type 2 diabetic patients who participated in clinical trials on diabetes mellitus was carried out. The clinical trials have been approved by the institutional ethics committee. Patient population included both males and females. Patients who underwent baseline hemogram profile were included for the study. Laboratory parameters collected include hemoglobin, hematocrit value, mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), red cell distribution width (RDW), glycosylated hemoglobin, serum creatinine, and urine albumin. Results: A total of 127 elderly patients with age >60 years and 122 patients with age below 60 years were included in the study. Mean hemoglobin concentration in elderly was 13.1 g/dL and in younger patients was 14.8 g/dL. The differences in the hemogram values among the two populations showed statistical significance only for hematocrit (P = 0.03) and RDW (P = 0.002). There was significant positive correlation between hemoglobin level and creatinine clearance (P = 0.019) and between hemoglobin and urine albumin concentration (P = 0.035) among elderly patients. Among the elderly patients 25 (19.7%) had anemia (hemoglobin below 12 g/dL), and 18 (14.8%) younger patients had anemia. Chi-square analysis did not show significance for distribution of anemia among the two populations. Conclusion: There was significant difference in the hemogram profile of elder and younger diabetics; levels were much less in elderly patients.

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